Here is an interesting example of a highly abstracted wireframe, labelled as a WireMolecule. Both the position and size of the represented elements within this example no longer represent what the interface will really look like. Instead, the focus has been shifted to showing relationships between elements as denoted by their proximity to each other. The size I also believe represents the importance of each element and not the actual size either (as also seen here and here). Definitely something a little different from a traditional wireframe. Andreas writes:
Traditional wire frames are misleading as they look too much like finished designs. Clients and designers alike run the risk of taking their direction too literally. And yet, despite all this, wire frames are invaluable tools in the start of any website design project.
And defines a WireMolecule as:
A chart giving an overview of relationships between components and features of a website. Wire molecules are developed during the Website Discovery phase and they provide instructions to designers, developers, and clients for how pages will look and behave.